LORELAI: Pale means sickly.
LUKE: Or sunscreen.
LORELAI: Or mad cow disease.
Bovine spongiform encephalopathy (BSE), commonly known as mad cow disease, is an incurable and inevitably fatal neurodegenerative disease of cattle. It can be spread to humans if they eat meat from infected cows.
In humans, infection can result in Creutzfeldt–Jakob disease (CJD), also known as subacute spongiform encephalopathy or neurocognitive disorder due to prion disease, an invariably fatal degenerative brain disorder. Early symptoms include memory problems, behavioral changes, poor coordination, and visual disturbances. Later symptoms include dementia, involuntary movements, blindness, weakness, and coma. About 70% of people die within a year of diagnosis. Pale skin isn’t one of the symptoms.
There was an outbreak of mad cow disease in the UK which lasted from 1986 to 2015, reaching a peak in 1993. There were a few cases in North America from 1993 to 2012, which had an impact on the US beef industry.