RORY: He’ll like whatever you get him.
LORELAI: If I slip him a Quaalude, he’ll like whatever I get him.
Quaalude is the old brand name in the US for the sedative Methaqualone; Quaalude is a portmanteau word combining “quiet interlude”. It was so readily available in the US that it was handed out at semi-legal “stress clinics” in the 1970s and ’80s. The drug was discontinued in the US in 1985 due to concerns about recreational abuse of the drug, which gave it a very bad reputation.
The Annotated Gilmore Girls 