LUKE: It’s just like all the other times Rachel. You’re the anywhere but here girl, you’re restless, you’re bored, it is what it is.
RACHEL: That’s not it.
A possible reference to the 1999 comedy-drama film Anywhere But Here, directed by Wayne Wang, and based on the prize-winning novel of the same name by Mona Simpson. The story is about an eccentric mother and her practical teenage daughter, with Susan Sarandon and Natalie Portman in the main roles. The film was successful and received good reviews.
It seems a bit unlikely as a film that Luke would go to see, but fits in with the timeline and themes of Gilmore Girls. If would certainly be very interesting if Luke had made an effort to see a film about a mother and teenage daughter.
The Annotated Gilmore Girls 